The UK Health Security Agency (UKHSA) has confirmed a new strain of mpox in England (on 8th December 2025). This was detected in an individual who had recently travelled to Asia, and genomic testing revealed the virus contains elements from two different mpox clades (Ib and IIb).
This isn’t unexpected – viruses evolve all the time – but it’s a reminder that mpox is still out there and can change. UKHSA is continuing to monitor the situation closely and share findings with global health partners, including the World Health Organization (WHO).
Reminder: what is mpox?
Mpox (previously known as monkeypox) is a rare viral infection. It is related to smallpox but less severe. The most common symptoms of mpox include fever, muscle aches, chills and exhaustion, headaches, swollen lymph nodes and a rash. You can learn more about mpox here.
Why this matters
Although mpox infection is mild for many, it can be severe. Vaccination remains the best way to protect yourself against serious illness. Studies show the mpox vaccine is around 75–80% effective – so if you’re eligible, now’s the time to get your jab.
Who can get the vaccine?
The mpox vaccination programme is available for people at higher risk, including those who:
- Have multiple sexual partners
- Take part in group sex
- Visit sex-on-premises venues
If you think you might have mpox symptoms, contact NHS 111 for advice.
Where can I get the vaccine?
The mpox vaccine is available in sexual health services. You might be offered a vaccine during another clinic appointment, such as for testing or treating an STI. If you would like the vaccine and think you’re eligible, call your local sexual health service. The person you speak to there can check if you’re eligible.
For more information on mpox, the vaccine, eligibility and sexual health services, visit the NHS mpox vaccine page.
